It was assigned to the Chicago-Kansas City passenger service in November 1937.
By the end of January 1938, the locomotive and its fellow locomotives were assigned to the aforementioned Chicago-LaJunta pool, and was often responsible for hauling Trains 7-8, the Fast Mail Express.
Locomotive 3463 remained assigned to service on the Illinois Division, though it was transferred to the Chicago – Newton, Kansas, passenger pool in 1947.
The last regular passenger service locomotive 3463 was assigned to was ATSF Trains 27-28, the Antelope, which operated between Kansas City and Oklahoma City This route was dieselized on March 18, 1953, causing 3463 to be bumped from regular passenger service.
Today its on static display on the grounds to the Southeast of the Kansas Expocentre in Topeka, Kansas.
When it was built for the railroad it went through a similar set of testing and trials as locomotive 3461, which had been received earlier that month.
By April of that year, locomotive 3463 was transferred to the Eastern Division, which stretched from Oklahoma City to Kansas City via Newton.
The locomotive's assignment lasted through WWII until dieselization of Trains 7-8 in late 1946.